Meditation maintains TCD4+ and TCD8+ lymphocyte levels and viral load constant in people living with HIV during the COVID-19 pandemic

Authors

DOI:

https://doi.org/10.21527/2176-7114.2023.47.13951

Keywords:

HIV,, meditation,, TCD4 and TCD8 lymphocytes.

Abstract

Background: The meditation can be a strategy for coping with psycho-emotional and physical comorbidities, that affect people living with HIV (PLWH), and that can be exacerbated in Covid-19 pandemic. Aim: To evaluate the levels of TCD4+ and TCD8+ cells, viral load, and metabolic parameters of PLWH submitted to meditation sessions. Experimental procedure: Case-crossover study in which 07 (seven) participants attended guided meditation sessions remotely, between July and August 2020 (8 weeks), one session per week, with an average duration of 1h each. Quantification of TCD4+ and TCD8+ lymphocytes was performed by flow cytometry; the viral load was detected by the polymerase chain reaction technique and the metabolic parameters by chemiluminescence. Results: Meditation kept the levels of TCD4+ (p=0.93) and TCD8+ (p=0.37) and viral load (<40) lymphocytes constant. Was observed an increase in high density lipoprotein-cholesterol (HDL-c) (p=0.01*), however glucose (p=0.15), triglycerides (p=0.43), total cholesterol (p=0.18), Glutamic Oxaloacetic Transaminase (p=0.46) and Glutamic Pyruvic Transaminase (p= 0.36) did not change. Conclusion: Meditation increases HDL-c in PLWH. The TCD4+ and TCD8+ lymphocyte levels and viral load remained constant during the intervention. The adherence to application of meditation can translate into a greater commitment to the search for health, and thus, improve the quality of life of these individuals.

References

Basso JC, Mchale A, Ende V, Oberlin DJ, Suzuki WA. Brief, daily meditation enhances attention, memory, mood, and emotional regulation in non-experienced meditators. Behavioural Brain Research. 2019; 356:208-220.

Ricard M, Lutz A, Davidson R. En el cerebro del meditador. Investigación y ciencia. 2015 May 20;(428):18-25.

Phillips KD, Sowell RL, Rojas M, et al. Physiological and psychological correlates of fatigue in HIV disease. Biological research for nursing. 2004;6(1):59-74. DOI: 10.1177/1099800404264846

Schuster R, Bornovalova M, Hunt E. The influence of depression on the progression of HIV: direct and indirect effects. Behavior modification. 2012;36(2):123-45. DOI: 10.1177/0145445511425231

Bernard C, Dabis F, Rekeneire N. Prevalence and factors associated with depression in people living with HIV in sub-Saharan Africa: a systematic review and meta-analysis. Plos One. 2017;1-22.

Marc I, Toureche N, Ernst E, et al. Mind-body interventions during pregnancy for preventing or treating women's anxiety. The Cochrane database of systematic reviews vol. 2011,7 CD007559. 6 Jul. 2011, DOI: 10.1002/14651858.CD007559.pub2

Greenlee H, DuPont-Reyes MJ, Balneaves LG, et al. Clinical Practice Guidelines on the Evidence-Based Use of Integrative Therapies During and After Breast Cancer Treatment. A cancer journal for clinicians. 2017;24:194-232.

Ramirez-Garcia MP, Gagnon MP, Colson S, et al. Mind-body practices for people living with HIV: a systematic scoping review. Bmc Complementary Medicine And Therapies. 2019;125(19):1-30.

Creswell JD, Myers HF, Cole SW, et al. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain, Behavior, And Immunity. 2009;23(2):184-188.

Mittleman MA, Madura M, Robins JM. Control Sampling Strategies for Case-Crossover Studies: An Assessment of Relative Efficiency. American Journal of Epidemiology. 1995;142(1):91-98.

Bastos FI, Lowndes CM, Santos EM. Características Sociodemográficas, Comportamentais e Vulnerabilidade à Infecção pelo Vírus da Imunodeficiência Humana em Homens que fazem Sexo com Homens do "Projeto Rio" [Doctoral Thesis]. Fundação Oswaldo Cruz; 2001.

Ben-Aicha S, Badimon L, Vilahur G. Advances in HDL: muito mais do qumuch more than lipid transporterse transportadores de lipídios. International Journal Of Molecular Sciences. 2020;1-18.

Yadav RK, Magan D, Yadav R, et al. High-density lipoprotein cholesterol increases following a short-term yoga-based lifestyle intervention: A non-pharmacological modulation. Acta Cardiologica. 2017;(23)69.

Renzo LD, Gualtieri P, Pivari F, et al. Eating habits and lifestyle changes during COVID-19 lockdown: an Italian survey. Journal of Translational Medicine. 2020;1-15.

Ammar A, Brach M, Trabelsi K, et al. Effects of COVID-19 Home Confinement on Eating Behaviour and Physical Activity: Results of the ECLB-COVID19 International Online Survey. Nutrients vol. 12,6 1583. 28 May. 2020. DOI: 10.3390/nu12061583

ASSADI SN. What are the effects of psychological stress and physical work on blood lipid profiles? Medicine. 2017;96(18):1-6.

Catalina-Romero C, Calvo E, Sánchez-Chaparro A, et al. The relationship between job stress and dyslipidemia. Scandinavian Journal of Public Health. 2013;(2):142-149.

Henriksen RE, Nilsen RM, Strandberg RB. Loneliness as a risk factor for metabolic syndrome: results from the hunt study. J Epidemiol Community Health. 2019:1-6.

Floyd K, Veksler AE, McEwan B. Social Inclusion Predicts Lower Blood Glucose and Low-Density Lipoproteins in Healthy Adults. Health Communication. 2016;56(8):1-4.

Silva AP, Vallim CA. Relação do estresse com a imunidade. Revista de iniciação científica da universidade vale do rio verde vol8,2; 2018.

Taiyi JMD, Jianhua HMS, Runsong SMSW, et al. Immunological and Psychological Efficacy of Meditation/Yoga Intervention Among People Living With HIV (PLWH): A Systematic Review and Meta-analyses of 19 Randomized Controlled Trials. Ann. Behav. Med.; 2020.

Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2003 Jan,;26(Suppl 1):S5-S20.

Faludi AA, Izar MCO, Saraiva JFK, Chacra APM, Bianco HT, Afiune Neto A et al. Atualização da Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose – 2017. Arq Bras Cardiol 2017;109(2Supl.1):1-76.

Kidney Disease Improving Global Outcomes. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int Suppl. [Internet]. 2013 [acessado em: 11 jan. 2018];3(1):1-150.

Tinsay A. Woreta, Saleh A. Alqahtani. Evaluation of Abnormal Liver Tests, Medical Clinics of North America. 2014;98(Issue 1):1-16. ISSN 0025-7125. ISBN 9780323287128

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Published

2023-12-12

How to Cite

Furtado, D. C., de Barros, E. . R., Porto, G. de S. M., Correia, L. M. T. D., de Almeida, V. D., de Oliveira, L. C., Fernandes, T. A. A. de M., do Nascimento, E. G. C. ., Nelson, I. C. A. de S. R., & de Andrade, M. F. (2023). Meditation maintains TCD4+ and TCD8+ lymphocyte levels and viral load constant in people living with HIV during the COVID-19 pandemic. Revista Contexto &Amp; Saúde, 23(47), e13951. https://doi.org/10.21527/2176-7114.2023.47.13951

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