Prevalence and factors associated with chronic kidney disease in diabetic patients

Authors

DOI:

https://doi.org/10.21527/2176-7114.2024.48.14221

Keywords:

Chronic kidney disease. Diabetes mellitus. Associated factors. Prevalence., Associated factors, Prevalence

Abstract

Introduction: The incidence of chronic kidney disease (CKD) has been increasing worldwide as a result of demographic and epidemiological transition processes, life expectancy, and the lack of control of chronic diseases, such as diabetes mellitus (DM). Thus, the present study aimed to evaluate the prevalence and factors associated with CKD in diabetic patients. Method: This was a cross-sectional study with diabetic patients enrolled in the Family Health Strategy (FHS), in the urban area of Rio Branco, state of Acre, in 2019. CKD was defined by GFR < 60 mL/1.72m², estimated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, or the presence of albuminuria > 29 mg/g. Measures of association were estimated by logistic regression, with a confidence level of 95%. Results: The prevalence of CKD was 40.0% in diabetic patients. A statistically significant association was found between CKD and treatment time longer than 10 years (1.74; 95%CI: 1.01; 3.02) and DM diagnosis (1.87; 95%CI: 1.05; 3.33) after adjustment. Conclusion: CKD has a high prevalence in diabetic patients, highlighting the need for public health measures for early detection and prevention of its progression.

References

Ogurtsova K, Guariguata L, Barengo NC, Ruiz PLD, Sacre JW, Karuranga S et al. IDF diabetes Atlas: Global estimates of undiagnosed diabetes in adults for 2021. Diabetes Res Clin Pract [Internet]. 2022 Jan [cited 2023 Jan 12]; 103(2): 109118. Available from: https://doi.org/10.1016/j.diabres.2021.109118.

Guariguata L, Whiting DR, Hambleton I, Beagley J, Linnenkamp U, Shaw JE. Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Res Clin Pract [Internet]. 2014 Feb [cited 2022 Aug 21]; 103(2):137-49. Available from: https://pubmed.ncbi.nlm.nih.gov/24630390/.

Hill NR, Fatoba ST, Oke JL, Hirst JA, O'Callaghan CA, Lasserson DS, et al. Global Prevalence of Chronic Kidney Disease - A Systematic Review and Meta-Analysis. PLoS One [Internet]. 2016 Jul 6 [cited 2022 Aug 13];11(7):e0158765. Available from: https://doi.org/10.1371/journal.pone.0158765.

de Boer IH, Caramori ML, Chan JCN, Heerspink HJL, Hurst C, Khunti K, et al. Executive summary of the 2020 KDIGO diabetes management in CKD guideline: evidence-based advances in monitoring and treatment. Kidney Int [Internet]. 2020 Oct [cited 2022 Sep 03];98(4):839–48. Available from: https://pubmed.ncbi.nlm.nih.gov/32653403/.

GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet [Internet]. 2020 Feb 29 [cited 2022 Sep 19]; 395:709–733. Available from: https://pubmed.ncbi.nlm.nih.gov/32061315/.

Liyanage T, Ninomiya T, Jha V. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet [Internet]. 2015 May 16 [cited 2022 Sep 30]; 385:1975–1982. Available from: https://pubmed.ncbi.nlm.nih.gov/25777665/.

Bailey RA, Wang Y, Zhu V, Rupnow MF. Chronic kidney disease in US adults with type 2 diabetes: an updated national estimate of prevalence based on Kidney Disease: Improving Global Outcomes (KDIGO) staging. BMC Res Notes [Internet]. 2014 Jul 2 [cited 2022 Oct 01]; 7:415. Available from: https://pubmed.ncbi.nlm.nih.gov/24990184/.

Jitraknatee J, Ruengorn C, Nochaiwong S. Prevalence and Risk Factors of Chronic Kidney Disease among Type 2 Diabetes Patients: A Cross-Sectional Study in Primary Care Practice. Sci Rep [Internet]. 2020 Apr 10 [cited 2022 Oct 01]; 10(1):6205. Available from: https://pubmed.ncbi.nlm.nih.gov/32277150/.

Aguiar LK, Ladeira RM, Machado ÍE, Bernal RTI, Moura L, Malta DC. Fatores associados à doença renal crônica segundo critérios laboratoriais da Pesquisa Nacional de Saúde. Revista Brasileira de Epidemiologia [Internet]. 2020 Set 30 [cited 2022 Oct 01]; 23:e200101. Available from: https://doi.org/10.1590/1980-549720200101.

Amaral TLM, Amaral CA, Vasconcellos MTL, Monteiro GTR. Prevalência e fatores associados à doença renal crônica em idosos. Rev Saúde Pública [Internet]. 2019 Apr 26 [cited 2022 Oct 01]; 53:44. Available from: https://doi.org/10.11606/S1518-8787.2019053000727.

Levey AS, Becker C, Inker LA. Glomerular filtration rate and albuminuria for detection and staging of acute and chronic kidney disease in adults: a systematic review. JAMA [Internet]. 2015 Feb 24 [cited 2022 Set 03]; 313(8):837-46. Available from: https://doi.org/10.1001/jama.2015.0602.

Alves LF, Abreu TT, Neves NCS, Morais FA, Rosiany IL, Oliveira Júnior WV, Pinto SWL, et al. Prevalência da doença renal crônica em um município do sudeste do Brasil. Braz J Nephrol [Internet]. 2017 Jun 21 [cited 2022 Oct 14]; 39(2):126-34. Available from: https://www.bjnephrology.org/article/prevalencia-da-doenca-renal-cronica-em-um-municipio-do-sudeste-do-brasil.

Hoogeveen EK. The Epidemiology of Diabetic Kidney Disease. Kidney Dial [Internet]. 2022 Ago 01 [cited 2022 Oct 14]; 2(3):433-442. Available from: https://doi.org/10.3390/kidneydial2030038.

Pinho NA, Silva GV, Pierin AMG. Prevalência e fatores associados à doença renal crônica em pacientes internados em um hospital universitário na cidade de São Paulo, SP, Brasil. J Bras Nefrol [Internet]. 2015 Jan 01 [cited 2022 Oct 17]; 37(1): 91-7. Available from: https://doi.org/10.5935/0101-2800.20150013.

Manski-Nankervis JE, Thuraisingam S, Lau P, Blackberry I, Sluggett JK, Ilomaki J, et al. Screening and diagnosis of chronic kidney disease in people with type 2 diabetes attending Australian general practice. Aust J Prim Health [Internet]. 2018 Jul 04 [cited 2022 Oct 17]; 24(3):280-6. Available from: https://pubmed.ncbi.nlm.nih.gov/29807557/.

Soman S, Areekal B, Varghese R, John S, Gopan RS, Jacob QM, et al. Chronic kidney disease-prevalence and determinants among type 2 diabetes mellitus patients attending a primary care setting in central Kerala. IJCMPH [Internet]. 2018 Jun 22 [cited 2022 Oct 17]; 5(7):2776. Available from: https://doi.org/10.18203/2394-6040.ijcmph20182453.

Rodriguez-Poncelas A, Garre-Olmo J, Franch-Nadal J, Diez-Espino J, Mundet-Tuduri X, Barrot-De la Puente J, et al. Prevalence of chronic kidney disease in patients with type 2 diabetes in Spain: PERCEDIME2 study. BMC Nephrol [Internet]. 2013 Feb 22 [cited 2022 Oct 20];1 4:46. Available from: https://doi.org/10.1186/1471-2369-14-46.

Lira DGD, Maio R, Burgos MGPA, Lemos MCC, Compagnon MC, Silva RP. Fatores associados à taxa de filtração glomerular em pacientes com diabetes mellitus tipo 2 atendidos em hospital universitário no nordeste do Brasil. Nutr clín diet hosp [Internet]. 2016 Mar 30 [cited 2022 Oct 21]; 36(2): 111-23. Available from: https://pesquisa.bvsalud.org/portal/resource/en;/ibc-153513.

González BS, Pascual MR, Guijarro LR, González AF, Puertolas OC, Latre LMR. Enfermedad renal crónica en Atención Primaria: prevalencia y factores de riesgo asociados. Atención Primaria [Internet]. 2015 Apr 01 [cited 2022 Oct 21]; 47(4):236-45. Available from: https://doi.org/10.1016/j.aprim.2014.06.003.

Hiraki K, Yasuda T, Hotta C, Izawa KP, Morio Y, Watanabe S et al. Decreased physical function in pre-dialysis patients with chronic kidney disease. Clin Exp Nephrol [Internet]. 2013 Apr 01[cited 2022 Oct 21]; 17(2):225-31. Available from: https://pubmed.ncbi.nlm.nih.gov/22911116/.

WILKINSON, T. J.; SHUR, N. F.; SMITH, A. C. "Exercise as medicine" in chronic kidney disease. Scand J Med Sci Sports [Internet]. 2016 Aug 23 [cited 2022 Oct 22]; 26(8):985-8. Available from: https://pubmed.ncbi.nlm.nih.gov/27334146/

BASTOS MG, KIRSZTAJN GM. Doença renal crônica: importância do diagnóstico precoce, encaminhamento imediato e abordagem interdisciplinar estruturada para melhora do desfecho em pacientes ainda não submetidos à diálise. Braz J Nephorol [Internet]. 2011 Mar 01 [cited 2022 Oct 23]; 33(1):93-108. Available from: https://doi.org/10.1590/S0101-28002011000100013.

Morton RL, Schlackow I, Staplin N, Gray A, Cass A, Haynes R, et al. Impact of Educational Attainment on Health Outcomes in Moderate to Severe CKD. Am J Kidney Dis [Internet]. 2016 Jan 01 [cited 2022 Oct 23]; 67(1):31-9. Available from: https://pubmed.ncbi.nlm.nih.gov/26385817/.

Green JA, Cavanaugh KL. Understanding the influence of educational attainment on kidney health and opportunities for improved care. Am J Kidney Dis [Internet]. 2016 Jan 16 [cited 2022 Oct 25]; 67(1):31-9. Available from: https://doi.org/ 10.1053/j.ackd.2014.07.004.

Park S, Lee S, Kim Y, Lee Y, Kang MW, Kim K, et al. Causal effects of education on chronic kidney disease: a Mendelian randomization study. Clin Kidney J [Internet]. 2020 Dec 22 [cited 2022 Oct 25]; 14(8):1932-8. Available from: https://pubmed.ncbi.nlm.nih.gov/34345417/.

Gatwood J, Chisholm-Burns M, Davis R, Thomas F, Potukuchi P, Hung A, et al. Evidence of chronic kidney disease in veterans with incident diabetes mellitus. PLoS One [Internet]. 2018 Feb 9 [cited 2022 Oct 25]; 13(2): e0192712. Available from: https://pubmed.ncbi.nlm.nih.gov/29425235/.

Spoto B, Pisano A, Zoccali C. Insulin resistance in chronic kidney disease: a systematic review. Am J Physiol Renal Physiol [Internet]. 2016 Dec 01 [cited 2022 Oct 26]; 311(6): F1087-F1108. Available from: https://pubmed.ncbi.nlm.nih.gov/27707707/.

Schrauben SJ, Cavanaugh KL, Fagerlin A, Ikizler TA, Ricardo AC, Eneanya ND et al. The Relationship of Disease-Specific Knowledge and Health Literacy With the Uptake of Self-Care Behaviors in CKD. Kidney Int Rep [Internet]. 2019 Oct 17 [cited 2022 Oct 26]; 5(1):48-57. Available from: https://pubmed.ncbi.nlm.nih.gov/31922060/.

Amorim RG, Guedes GS, Vasconcelos SML, Santos JCF. Kidney Disease in Diabetes Mellitus: Cross-Linking between Hyperglycemia, Redox Imbalance and Inflammation. Arq Bras Cardiol [Internet]. 2019 May 10 [cited 2022 Oct 26]; 112(5): 577-87. Available from: https://doi.org/10.5935/abc.20190077.

Levin A, Stevens PE, Bilous RW, Coresh J, Francisco ALM, Jong PE, et al. Kidney disease: Improving global outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International Supplements [Internet]. 2013 Jan 01 [cited 2022 Jun 14]; 3(1):1-150. Available from: https://doi.org/10.1038/kisup.2012.73.

Published

2024-03-27

How to Cite

Ualison Oliveira, Monteiro, G. T. R. ., Amaral, C. de A., de Vasconcellos , M. T. L., & Amaral, T. L. M. (2024). Prevalence and factors associated with chronic kidney disease in diabetic patients . Revista Contexto &Amp; Saúde, 24(48), e14221. https://doi.org/10.21527/2176-7114.2024.48.14221

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Section

ORIGINAL ARTICLE